Detection The Polymorphism in exon- 6 for gene PPAR-ᵧ in Obese Polycystic Ovarian Syndrome Women

Peroxisome Proliferator Activated Receptors Gamma (PPAR-ᵞ) is a nuclear transcription factor, which Protein receptors for insulin and have significant role in resistance Type 2 Diabetes mellitus addition to the of gene encoded differentiation Adipocyte development Adipose tissue. at present research has been detected substitution silent mutation C T exon 6 PPAR-ᵧ 111 women, including 73 obese women with Polycystic ovarian syndrome 38 healthy . we determined certain biochemical variables (Blood Sugar, HDL-C, Triglycerides) find body mass index (BMI) compared between two groups where results showed difference value BMI concentration each (0.05 0.01) among Patient Healthy mutant allele frequency them The Obese PCOS was (0.336) (0:29) this indicates correlation disease